I did not like Love and Other Drugs. The movie is based on Hard Sell: The Evolution of a Viagra Salesman by Jamie Reidy, a former Pfizer rep. Loosely, I believe, because the book lacks any love interest... It was a starting point at least. The movie took a very negative view of doctors and the pharmaceutical industry.
I had issues with the morality of many of the characters. One of the questions I overheard in the theater was ‘what was the difference between the movie and a porno?’ It was meant as a joke but there was a ton of nudity and frankly I don’t understand why Anne Hathaway had to bare skin in the film at all. I didn’t think there was much difference between Anne showing darn near everything and the girl who was on screen for two minutes allowing Josh Gad’s character to hump her in a parody of sex.
(Why did Josh’s character exist at all, really? Incidentally the character's name is Josh too.)
I was unaware of the Parkinson's Disease side of the story because I went off the theatrical trailer only and didn’t bother to check anything out before going to the theaters. I think Anne Hathaway acted really well. It was very hard/uncomfortable to watch her hands jitter and her bad days. It was a very depressing side to the story.
Actually I felt the movie couldn’t decide if it was a comedy or a drama. There were some light moments but everything happy was overshadowed by a lot of negatives.
Minor Spoiler: The best part of the movie? Listening to Hank Azaria explain as Dr. Stan Knight why he wanted to be a doctor in the first place. It came across heartfelt and well received. I called Jake Gyllenhaal’s character going back to school from this scene alone... well that and he's desperate for a cure for Maggie Murdock (Anne Hathaway).
It ends on a happy for now note which is a good thing otherwise the whole experience would have been pointless.